There is no requirement to do anything in V-Ray once you open an Enscape scene - just opportunities. You can get a higher resolution, more output options, and higher ray tracing depths immediately.
Important Notice: Due to a high volume of inquiries, our response times may be delayed. We apologize for this, and appreciate your patience as our team works diligently to address your concerns. Thank you for your understanding! If you are experiencing licensing issues related to the Enscape 4.1 release, please visit our detailed FAQ document here